Methyl 5,6-dichloropyridine-3-carboxylate, 5,6-Dichloro-3-(methoxycarbonyl)pyridine
METHYL 5,6-DICHLORONICOTINATE
CAS: 56055-54-0
Molecular Formula: C7H5Cl2NO2
Methyl 5,6-dichloropyridine-3-carboxylate, 5,6-Dichloro-3-(methoxycarbonyl)pyridine - Names and Identifiers
Methyl 5,6-dichloropyridine-3-carboxylate, 5,6-Dichloro-3-(methoxycarbonyl)pyridine - Physico-chemical Properties
| Molecular Formula | C7H5Cl2NO2 |
| Molar Mass | 206.03 |
| Density | 1.426±0.06 g/cm3(Predicted) |
| Melting Point | 63-65°C |
| Boling Point | 265.5±35.0 °C(Predicted) |
| Appearance | Brown crystal |
| pKa | -2.84±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Methyl 5,6-dichloropyridine-3-carboxylate, 5,6-Dichloro-3-(methoxycarbonyl)pyridine - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Class | IRRITANT |
Methyl 5,6-dichloropyridine-3-carboxylate, 5,6-Dichloro-3-(methoxycarbonyl)pyridine - Upstream Downstream Industry
| Downstream Products | Methyl 6-chloronicotinate 3-Pyridinecarboxylicacid,5,6-dimethyl-(9CI) |
Methyl 5,6-dichloropyridine-3-carboxylate, 5,6-Dichloro-3-(methoxycarbonyl)pyridine - Introduction
METHYL 5,6-dichloronicotinate is an organic compound with the chemical formula C7H5Cl2NO2. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: METHYL 5,6-dichloronicotinate is a colorless liquid.
2. Solubility: It can be dissolved in most organic solvents, such as alcohols, ethers, chlorinated hydrocarbons, etc.
3. Melting point and boiling point: The melting point of METHYL 5,6-dichloronicotinate is about 68-71 degrees Celsius, and the boiling point is about 175 degrees Celsius.
Use:
1.METHYL 5,6-dichloronicotinate can be used as an intermediate in organic synthesis and used in the synthesis of other organic compounds.
2. It can also be used in the fields of pesticides, medicines and dyes.
Method:
The synthesis method of METHYL 5,6-dichloronicotinate can be achieved through the following steps:
1. First, nicotinic acid (nicotinic acid) reacts with thionyl chloride (thionyl chloride) to generate nicotinic acid chloride (nicotinoyl chloride).
2. Then, nicotinic acid chloride is reacted with methanol to produce METHYL 5,6-dichloronicotinate.
Safety Information:
1. METHYL 5,6-dichloronicotinate is an organic compound that is irritating. Avoid direct contact with skin and eyes during use or contact.
2. During operation, it is necessary to ensure good ventilation conditions and avoid inhaling its steam.
3. When storing and handling, it should be kept away from fire and oxidant.
4. In case of accidental inhalation or contact, immediately flush the affected area with plenty of water and seek medical help.
5. When using METHYL 5,6-dichloronicotinate, Please strictly abide by the relevant safety operation procedures and personal protective measures.
Nature:
1. Appearance: METHYL 5,6-dichloronicotinate is a colorless liquid.
2. Solubility: It can be dissolved in most organic solvents, such as alcohols, ethers, chlorinated hydrocarbons, etc.
3. Melting point and boiling point: The melting point of METHYL 5,6-dichloronicotinate is about 68-71 degrees Celsius, and the boiling point is about 175 degrees Celsius.
Use:
1.METHYL 5,6-dichloronicotinate can be used as an intermediate in organic synthesis and used in the synthesis of other organic compounds.
2. It can also be used in the fields of pesticides, medicines and dyes.
Method:
The synthesis method of METHYL 5,6-dichloronicotinate can be achieved through the following steps:
1. First, nicotinic acid (nicotinic acid) reacts with thionyl chloride (thionyl chloride) to generate nicotinic acid chloride (nicotinoyl chloride).
2. Then, nicotinic acid chloride is reacted with methanol to produce METHYL 5,6-dichloronicotinate.
Safety Information:
1. METHYL 5,6-dichloronicotinate is an organic compound that is irritating. Avoid direct contact with skin and eyes during use or contact.
2. During operation, it is necessary to ensure good ventilation conditions and avoid inhaling its steam.
3. When storing and handling, it should be kept away from fire and oxidant.
4. In case of accidental inhalation or contact, immediately flush the affected area with plenty of water and seek medical help.
5. When using METHYL 5,6-dichloronicotinate, Please strictly abide by the relevant safety operation procedures and personal protective measures.
Last Update：2024-04-09 21:01:54
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Downstream Products for Methyl 5,6-dichloropyridine-3-carboxylate, 5,6-Dichloro-3-(methoxycarbonyl)pyridine